Causes of invasive hydatidiform mole

The treatment of invasive hydatidiform mole requires chemotherapy, surgery or radiotherapy according to the condition. The cause of the disease is related to multiple factors such as genetics, environment, and physiology. Commonly used chemotherapy drugs include methotrexate, actinomycin D, and etoposide. Surgical methods include hysterectomy, curettage, and uterine artery embolization. Radiotherapy is suitable for local control.

1. Genetic factors: Some patients with invasive hydatidiform mole have chromosomal abnormalities, such as triploidy or partial hydatidiform mole, which may lead to excessive proliferation of trophoblasts. People with a family history of hydatidiform mole need to be vigilant and undergo regular gynecological examinations.

2. Environmental factors: Long-term exposure to harmful chemicals, radiation or living in a heavily polluted environment may increase the risk of disease. Pregnant women should avoid contact with harmful substances such as pesticides and heavy metals and keep their living environment clean.

3. Physiological factors: Physiological conditions such as pregnant women who are too old or too young, multiple pregnancies, and malnutrition may affect embryo development and lead to the formation of hydatidiform mole. During the period of preparing for pregnancy, you should maintain a balanced diet and supplement nutrients such as folic acid.

4. Trauma: External impact on the uterus or improper surgical operation may damage the endometrium and affect embryo implantation and development. Pregnant women should avoid strenuous exercise and pay attention to protecting their abdomen.

5. Pathological factors: Women with a history of hydatidiform mole, miscarriage, or uterine fibroids have a higher risk of developing invasive hydatidiform mole. Regular gynecological examinations can help to detect and treat related diseases at an early stage.

The causes of invasive hydatidiform mole are complex, involving genetic, environmental, physiological and other factors. Treatment requires chemotherapy, surgery or radiotherapy according to the specific situation. Early detection and intervention are crucial to prognosis.