What is an invasive hydatidiform mole and what causes it

What is an invasive hydatidiform mole and what causes it

Invasive hydatidiform mole is a gestational trophoblastic disease. Treatment requires timely surgical removal of the lesion, combined with chemotherapy when necessary. Its formation is related to multiple factors such as genetics, environment, and physiology.

1. Genetic factors: Some patients have chromosomal abnormalities, such as triploidy or tetraploidy, which lead to abnormal proliferation of trophoblastic cells and the formation of invasive hydatidiform mole. People with a similar medical history in their family need to be vigilant and undergo regular gynecological examinations.

2. Environmental factors: Long-term exposure to chemicals, radiation or living in a highly polluted environment may increase the risk of disease. During pregnancy preparation, you should avoid contact with harmful substances and maintain a healthy living environment.

3. Physiological factors: Too old or too young, multiple pregnancies, malnutrition, etc. may affect the normal development of trophoblasts and lead to the occurrence of diseases. Maintaining a balanced diet and supplementing folic acid and vitamins can help reduce the risk.

4. Pathological factors: Patients with a history of hydatidiform mole or miscarriage have a higher probability of developing invasive hydatidiform mole during the next pregnancy. Pregnancy management should be carried out under the guidance of a doctor and the condition should be closely monitored.

Treatment methods include surgical removal of the lesion, chemotherapy, and regular follow-up. Surgery usually involves curettage or hysterectomy, and chemotherapy drugs include methotrexate, actinomycin D, or etoposide. Blood HCG levels should be tested regularly after surgery to ensure that the condition is stable.

The prevention and treatment of invasive hydatidiform mole requires a combination of genetic, environmental, physiological and other factors. Early detection and intervention are key. Patients should actively cooperate with doctors for treatment, maintain good living habits, and have regular checkups to reduce the risk of recurrence.

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