The main causes of hydatidiform mole include genetic factors, environmental influences, and maternal physiology and pathology. Specifically, it is often caused by chromosomal abnormalities in the fertilized egg. Early identification of the cause and standardized treatment are the key. It is recommended that patients undergo drug elimination, follow-up monitoring, or surgical intervention when necessary. 1. Genetic factors The occurrence of hydatidiform mole is often related to chromosomal abnormalities. Complete hydatidiform mole often occurs due to abnormal fertilization between sperm and egg cells, which causes the embryo to fail to develop normally and forms partial or complete villous edema. Partial hydatidiform mole may be caused by abnormal sperm count, with more than two sperm entering the egg, resulting in polyploid chromosomal genetic defects. Families with fertility problems or a history of hydatidiform mole can receive genetic counseling before trying to conceive again. 2 Environmental factors Poor nutrition, lack of vitamin A, folic acid and trace elements are also possible causes of hydatidiform mole. Long-term malnutrition can damage the implanted embryo and increase the risk of "grape-like" lesions of the villi. It is recommended to maintain a healthy diet and consume more foods rich in vitamins and antioxidants, such as dark green vegetables and appropriate amounts of protein. 3 Maternal physiology and pregnancy-related effects Women who are over 35 years old, have advanced pregnancy or have a history of multiple miscarriages are more likely to have hydatidiform mole. Women of childbearing age who do not undergo a systematic physical examination before pregnancy may miss potential risks such as uterine infection and uterine malformation. During the period of preparing for pregnancy, reproductive health should be screened regularly and physical problems should be improved in a timely manner. 4 Pathological causes Certain long-term chronic diseases such as endometrial lesions or reproductive system inflammation may lead to embryo implantation failure or abnormal proliferation of trophoblastic cells, which in turn may induce hydatidiform mole. For women with a history of related diseases, intervention and conditioning should be carried out under the guidance of professional doctors to improve endocrine and uterine conditions. When facing hydatidiform mole, the most important thing is to quickly receive a doctor's diagnosis and provide corresponding treatment. Common treatment methods include surgical curettage, drug-assisted treatment, and chemotherapy to prevent malignant transformation. Regular follow-up and close monitoring of serum hCG indicators ensure the removal of lesions and reduce the risk of recurrence. If you have related symptoms, you must seek medical attention as soon as possible to avoid delaying the condition. |
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