How to treat premature ovarian failure

Premature ovarian failure is a disease caused by multiple factors such as genetic factors and immune factors. Amenorrhea is a common symptom of patients' clinical manifestations. This type of disease will seriously affect the patient's normal work and life. Therefore, appropriate treatment must be carried out in time to ensure recovery of the disease as much as possible.

The first is estrogen-progesterone replacement therapy: estrogen-progesterone replacement therapy is very important for young POF patients, which can relieve the symptoms of low estrogen and urogenital atrophy (prepare for egg donation and embryo transplantation), prevent long-term complications (osteoporosis, Alzheimer's disease, etc.), and reduce the risk of colon cancer by 37%. But long-term HRT also has certain risks, such as the occurrence of endometrial cancer and breast cancer. However, studies have shown that estrogen-progesterone replacement therapy for more than 10 days a month can reduce the risk of endometrial cancer to almost zero, while the risk of breast cancer is slightly increased, but the mortality rate is not increased.

The second is immunotherapy: Since immune factors are the clear cause of premature ovarian failure, immunosuppressive therapy is effective for these patients with evidence of immune factors.

The treatment of premature ovarian failure should be comprehensive treatment based on the patient's cause and various factors, which is more conducive to the patient's health recovery.