What is the cause of congenital absence of vagina?

What causes congenital absence of vagina? Congenital absence of vagina is caused by the stagnation of the tail end of the paramesonephric duct during embryonic development and its failure to extend downward. Therefore, it is often accompanied by incomplete or undeveloped uterus, but the ovaries generally develop normally. So what causes congenital absence of vagina?

Patients with congenital absence of vagina have normal external genitalia, with or without a hymen, and a shallow depression or short lower vagina. Most patients with congenital anterior vagina have only a completely closed vaginal vestibule mucosa at the normal vaginal opening, with no vaginal traces. Some patients also have a shallow depression in the vaginal vestibule, and some have a blind vagina shorter than 3 cm. It is often accompanied by no deformity, and only slightly thickened strip-like tissue can be seen in the normal uterus, located in the middle of the broad ligament.

Causes of congenital absence of vagina:

1. Chromosome abnormality;

2. Infection with certain viruses or toxoplasma in early pregnancy;

3. The mother used male hormone anticancer drugs such as thalidomide in early pregnancy;

4. Androgen insensitivity syndrome.

Editor's message: I hope this article can help you gain a basic understanding of congenital absence of vagina. If you have the above symptoms, please check and treat them in time. I sincerely wish you good health and a happy life.