What is the cause of itching and atrophy of vulvar leukoplakia? What should I do?

Itching and atrophy of vulvar leukoplakia indicate the presence of white spots on the vulva, usually vulvar white lesions, which refer to a group of chronic diseases in which the pigmentation of the female vulvar skin and mucous membrane tissue changes. The cause is currently unknown and may be related to autoimmune reactions, genetic factors, trauma and chronic stimulation, endocrine factors, infection, etc. It is recommended to seek medical attention in time and take measures such as topical medications, phototherapy, oral medications, and local care under the guidance of a doctor.

1. Autoimmune reaction: Vulvar leukoplakia is a chronic skin disease with the main symptoms of itching, hypopigmentation of the vulvar skin and mucous membranes, or the appearance of hypopigmented white spots in the vulvar area. An autoimmune reaction is a situation in which the body's immune system mistakenly attacks its own tissues. The autoimmune reaction may cause damage or destruction of pigment cells, thus causing the formation of white spots. You can follow the doctor's advice to use topical triamcinolone acetonide ointment, fluocinolone ointment, tacrolimus ointment and other drugs for treatment, which can help control symptoms and promote skin recovery.

2. Genetic factors: Genetic factors may play a role in the occurrence of vulvar leukoplakia. Studies have shown that certain gene mutations may increase an individual's risk of developing vulvar leukoplakia. In this case, it is recommended to seek medical attention in a timely manner. After a clear diagnosis, you can follow the doctor's advice to use topical medications or phototherapy for treatment, such as triamcinolone acetonide ointment, fluocinolone ointment, or use ultraviolet rays of a specific wavelength to irradiate the affected skin to promote the production and recovery of pigments.

3. Trauma and chronic irritation: Trauma, chronic irritation or friction in the vulva area, such as not paying attention to personal hygiene, not taking a bath frequently or wearing poor quality underwear, may cause damage to local tissues and destruction of pigment cells, leading to the formation of white spots. In this case, you need to pay attention to the cleanliness and hygiene of the vulva area, avoid using irritating lotions, choose cotton, non-irritating underwear, take a bath frequently, etc., to reduce irritation and improve the condition.

4. Endocrine factors: Disorders of the endocrine system, such as abnormal thyroid function or changes in estrogen levels, may be related to the occurrence of white lesions on the vulva. Patients with hyperthyroidism can be treated with drugs such as propylthiouracil tablets and methimazole tablets after a clear diagnosis by a doctor. Patients with hypothyroidism can take drugs such as levothyroxine sodium tablets, Yikang capsules, and thyroid tablets as prescribed by a doctor to promote the secretion of thyroid hormones. Patients with changes in estrogen levels can supplement with drugs such as oryzanol tablets, estradiol tablets/estradiol dydrogesterone tablets combined packaging as prescribed by a doctor for regulation.

5. Infection: Certain infections, such as fungal infection, bacterial infection, viral infection, etc., may cause immune response and tissue damage, and also lead to the occurrence of vulvar leukoplakia. When the symptoms of vulvar leukoplakia are severe, you can follow the doctor's advice to take oral medications, such as Bailing Tablets, Vitamin E Soft Capsules, Fluconazole Capsules, etc., to promote pigment recovery or improve symptoms.

For severe cases, surgical treatment may also be considered, such as skin transplantation or surgical excision. Avoid eating spicy and allergic foods, change to loose and comfortable underwear, and wash underwear frequently. During treatment, adjust your mental state, reduce your psychological burden, maintain a stable mentality, and see a doctor regularly for follow-up to understand your recovery.