The causes of fetal miscarriage may first be fetal reasons, such as abnormal fetal development and placental development; secondly, it may be external reasons or immune privacy; finally, it may be maternal factors, such as acute infectious diseases, diseases, endocrine disorders, mental stimulation, and relaxation of the internal cervical os, etc. We know that pregnancy is a very complicated process. In this process, there are many things that need to be done with special care, otherwise it is easy to induce accidents, causing serious harm to the health of the fetus and the pregnant woman, such as miscarriage. Let us understand the causes of miscarriage! 1. Fetal factors 1. Abnormal embryonic development <br/>Fetal developmental abnormalities are the most common cause of early miscarriage, and miscarriages caused by chromosomal abnormalities account for about 50% to 60%. 2. Placental abnormalities <br/>Due to incomplete development of the trophoblast, degeneration of the placental villi, or the placenta being attached too low, fetal-placental circulation may be impaired, leading to miscarriage. 2. Maternal factors 1. Acute infectious diseases <br/>Some diseases can cause fetal death due to pathogens or toxins invading through the placenta, or cause uterine contractions and miscarriage due to high fever or poisoning. 2. Disease factors <br/>Some factors such as severe anemia or heart failure can lead to fetal death due to lack of oxygen; uterine hypoplasia and uterine fibroids or malformations can also hinder embryonic development. 3. Endocrine disorders <br/>If a pregnant woman has endocrine disorders, such as luteal insufficiency and decidual dysplasia, it will affect the development of the fertilized egg. 4. Relaxation of the internal cervical os <br/>Sometimes the relaxation of the internal cervical os can cause late miscarriage because it cannot withstand the increased pressure of the fetal gestational sac. 5. Mental stimulation <br/>Some very strong mental stimulation can induce miscarriage, while trauma and sexual intercourse can also induce miscarriage. However, the common inducing factors are mainly caused by defects in the embryo itself. (III) External factors <br/>Toxic substances that induce miscarriage include: cadmium, lead and organic mercury, in addition, there are DDT and other radioactive substances, etc. These toxic substances may directly act on the fetal somatic cells, or they may affect the fetus through the placenta and cause miscarriage. (IV) Immune factors : After a woman becomes pregnant, due to immune incompatibility between mother and fetus, the mother rejects the fetus, which in turn leads to miscarriage. Relevant immune factors include: histocompatibility antigens of the spouse and fetal antigens, blood type antigens, imbalance of maternal cellular immune regulation, maternal blocking antibodies during pregnancy, and lack of maternal cytotoxic antibodies against paternal lymphocytes. |