Can B-ultrasound detect hyperprolactinemia?

Hyperprolactinemia (HPRL) is a common reproductive endocrine disease in women, with clinical manifestations mainly including menstrual disorders, infertility, galactorrhea, tumor compression symptoms and sexual function changes. Drug therapy is the main treatment for HPRL, so how to check is crucial to the treatment of HPRL.

1. Physical examination. Pay attention to vision, fingertips abnormalities, obesity, hypertension, hirsutism, and chest wall lesions. Pay attention to genital development, atrophy, or pelvic masses during pelvic examination. Pay attention to galactorrhea during breast examination, whether it is unilateral or bilateral, milk properties, and milk secretion. The milk collected under a low-power microscope shows fat droplets, which are milk.

2. Blood PRL level measurement The best time to collect blood is between 9 and 11 am in a quiet state. PRL greater than 25up/L is high PRL. If the PRL value is greater than 50ug/L, the incidence of pituitary microadenoma is about 25%. When PRL is greater than 250up/L, the possibility of pituitary macroadenoma is high.

3. Imaging blood tests can detect pituitary microadenomas through enhanced magnetic resonance imaging and enhanced computed tomography.

4. Visual field examination: Pituitary tumors may invade or compress the optic chiasm, leading to visual field defects. The manifestations of visual field defects may range from classic, complete bitemporal hemianopsia to small partial quadrant defects or scotomas.

5. Gynecological ultrasound is used to observe whether the shape and size of the uterus and ovaries are abnormal.