Surgical treatment of hyperprolactinemia

If you suffer from hyperprolactinemia during pregnancy, it will bring very serious harm. When we discover the disease, we must have reasonable treatment methods. Many times, we are not very clear about the treatment methods for hyperprolactinemia during pregnancy. Let's take a look at the following introduction!

Patients with hyperprolactinemia often come to the attention of obstetricians after a spontaneous pregnancy or with a history of hyperprolactinemia being treated for infertility. Pregnancy may present with a transient physiologic hyperprolactinemia. However, some clinical symptoms (such as lactation, anovulation, or hypogonadism) suggest that treatment should be sought; these symptoms are unrelated to pregnancy. Furthermore, idiopathic hyperprolactinemia and microadenomas rarely result in significant adverse outcomes. Therefore, enlargement of a macroadenoma is the most common indication for treatment during pregnancy. Treatment options include bromocriptine and transsphenoidal surgery.

Bromocriptine is an ergot derivative with potential dopamine agonist activity. In patients with hyperprolactinemia and anovulation treated with bromocriptine, 80% to 90% of them will have normal menstruation and many will be able to become pregnant. Side effects are also significant, with vomiting and postural hypotension being more common. Side effects are more frequent during initial treatment. Treatment starts with a low dose (1.25 mg) taken at bedtime with meals. After a few weeks, the dose can be increased to 2.5 mg twice a day, and the clinical effect can be evaluated after a few months. If you cannot tolerate the side effects, you can try vaginal bromocriptine.

In addition to improving the clinical symptoms of hyperprolactinemia (anoovulation, lactation, or hypogonadism), bromocriptine can also shrink prolactinomas.

What are the treatments for hyperprolactinemia during pregnancy? We are all very clear about it. We must take active treatment measures. In life, we must have a reasonable diet and reasonable health care. We must make a good diet plan. I wish the patients good health and a speedy recovery!