Endometrial repair method helps stop bleeding in anovulatory functional bleeding

Xiaoyun has always had irregular menstruation in the past year. Either the duration is too long or the bleeding does not stop. This makes her feel very depressed. Her husband, who is eager to have a child, complains about this and often blames this problem for their lack of children. He forces Xiaoyun to go to the hospital for a check-up. However, Xiaoyun is always too busy at work to have time. However, it doesn’t matter if she delays. This month, she has had her period for more than ten days and it is still heavy. Xiaoyun feels dizzy and has to take a leave to go to the hospital. As a result, Xiaoyun was diagnosed with anovulatory functional uterine bleeding. The doctor first used the endometrial repair method to help Xiaoyun stop bleeding. So what kind of treatment is this?

Endometrial repair method is to use a large amount of estrogen for treatment. The clinical effect of estrogen hemostasis method is positive. The principle of this hemostasis method is that estrogen can stimulate the rapid growth of the endometrium, repair the surface in a short period of time, and thus stop bleeding relatively quickly. In the past, the commonly used drug was estradiol benzoate, with an initial dose of 2~4mg intramuscular injection, which was repeated every 6-8h according to the bleeding situation until the bleeding stopped. It is also useful to use 25mg of pregnant horse estrone (Bemarle) intravenous or intramuscular injection 1~2 times to quickly stop bleeding. Now other estrogen preparations of corresponding doses are commonly used in clinical practice, such as oral administration of 2.5-5.0mg of pregnant horse estrone, once every 8h or estradiol valerate until bleeding stops, generally 1~3 days after bleeding stops. 2~3 days after the bleeding stops, the estrogen dose will be gradually reduced, each time by about 1/3 of the previous dose, and each reduction will be maintained for 2-3 days. Too fast a reduction will cause bleeding again. When the dose is reduced to 1-2 mg of estradiol per day or a dose equivalent to this (such as oral pregnant estrone 1.25 mg/d), this dose can be maintained until the anemia is significantly corrected and then the progesterone can be withdrawn. The usage is the same as the progesterone endometrial shedding method mentioned above.