Is adenomyosis related to amenorrhea?

Adenomyosis may cause amenorrhea, but not all patients will experience amenorrhea. This association is mainly related to the degree of the disease, changes in hormone levels and treatment methods. Specific causes may include abnormal uterine structure, endocrine disorders or drug factors used during treatment. If amenorrhea occurs, you need to seek medical attention in time to identify the cause and carry out personalized treatment.

1) Adenomyosis affects the structure of the uterus

Adenomyosis is a chronic disease caused by the invasion of endometrial glands and stroma into the myometrium, which can lead to thickening of the uterine wall and myometrial fibrosis. This structural abnormality may disrupt the normal function of the endometrium, affect the menstrual cycle, and even cause amenorrhea. For such factors, doctors may use surgical treatments, such as hysterectomy (suitable for women with severe symptoms and no longer fertile) or hysteroscopic surgery to improve the structure of the uterus. Patients who are discovered early can try to use medication to control the progression of the disease.

2) Endocrine disorders

The course of adenomyosis may cause hormonal disorders in the body, especially an imbalance in the ratio of estrogen and progesterone. Endocrine disorders can inhibit ovulation and menstrual cycles, further leading to amenorrhea. In mild cases, hormone levels can be adjusted through medication, such as sex hormone-releasing hormone (GnRH) agonists or progesterone drugs. This type of treatment is usually short-term, but it needs to be carried out under the guidance of a doctor to avoid side effects such as osteoporosis.

3) Drug intervention during treatment

Some treatments for adenomyosis may cause temporary amenorrhea, such as the use of GnRH agonists. These drugs inhibit ovarian function, reduce estrogen levels in the body, and simulate menopause to relieve symptoms. Although amenorrhea is a normal result of this treatment, it does not mean permanent damage, and menstruation usually returns to normal after stopping the drug. If the adverse reactions of the drug-induced amenorrhea are strong, you can seek guidance from your doctor to adjust the treatment plan, such as using a small dose of hormones in combination to avoid discomfort.

For patients with more severe symptoms or amenorrhea caused by other reasons, a comprehensive evaluation should be conducted under the guidance of a doctor and a personalized treatment plan should be developed. If amenorrhea is accompanied by symptoms such as persistent pain and abnormal bleeding, it is recommended that patients choose comprehensive treatment methods in a timely manner.

There is indeed a certain connection between adenomyosis and amenorrhea, but the causes are complex and vary from person to person. If amenorrhea occurs, the cause needs to be found and treated as soon as possible to avoid further impact on health. Maintaining regular gynecological examinations and paying attention to the normality of the menstrual cycle are important ways to protect women's reproductive health.