Drugs for the treatment of adenomyosis

The treatment of adenomyosis mainly includes analgesics, hormone drugs and gonadotropin-releasing hormone agonists, with the aim of relieving pain, controlling the disease and improving the patient's quality of life. Each drug has different indications and effects, and needs to be selected under the guidance of a doctor.

1) Pain medication

For mild to moderate pain, nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen and celecoxib, are commonly used. These drugs can relieve menstrual pain and chronic pelvic pain. When using them, pay attention to the dosage, take them according to the doctor's instructions, and avoid long-term use to prevent gastrointestinal irritation.

2) Hormone drugs

Hormonal therapy mainly works by reducing estrogen levels to inhibit the growth of the endometrium. Commonly used drugs include:

- Progestogen drugs: Dienogest is a commonly used choice, which relieves symptoms by inhibiting endometrial hyperplasia. It may cause reduced menstrual flow or amenorrhea when taken, but the effect is significant.

-Combined oral contraceptive pills: Suitable for patients with milder conditions, they can regulate hormone levels every month and relieve dysmenorrhea and excessive menstrual bleeding.

-Levonorgestrel intrauterine device (IUD): Local release of hormones, effective pain relief, suitable for patients who need long-term contraception.

3) Gonadotropin-releasing hormone (GnRH) agonists

This type of drug (such as leuprolide) reduces hormone levels by inhibiting ovarian function, simulating a "pseudo-menopause" state to improve adenomyosis, but its side effects include temporary menopausal symptoms such as bone loss and hot flashes. It is generally not used for more than 6 months, and is often combined with "add-on therapy" to reduce side effects.

Precautions and medication selection

Patients need to choose appropriate medications based on the severity of their condition, age, and fertility plans. If symptoms are mild, painkillers or hormone drugs can be used; for severe patients or those with poor drug tolerance, other treatments (such as surgery) should be considered.

Drug treatment for adenomyosis requires an individualized plan. If symptoms are severe or medication is ineffective, you should actively communicate with your doctor to adjust your treatment strategy, such as considering further intervention measures such as surgery. Do not stop or use medication without authorization.