Are the symptoms of hyperprolactinemia serious?

Hyperprolactinemia is the most common pituitary disease. The main predisposing factor is caused by changes in the internal and external environment. It is mainly manifested in high prolactin, generally greater than 25ng/ml. It is a syndrome characterized by amenorrhea, galactorrhea, anovulation and infertility. Hyperprolactinemia is characterized by galactorrhea and hypogonadism. If a woman suffers from hyperprolactinemia, she will show decreased libido and loss of sexual desire, which will be relieved after treatment as the PRL level decreases.

The most prominent manifestation of hyperprolactinemia is hypogonadism, which is caused by elevated PRL levels and is called hyperprolactinemic hypogonadism. Female patients may experience decreased libido and loss of sexual desire, which will be relieved after treatment as PRL levels decrease. In women of childbearing age, hyperprolactinemic hypogonadism is mainly manifested by decreased menstruation or even amenorrhea, but it can also be manifested as menorrhagia or normal menstruation with infertility.

Galactorrhea is another common symptom, seen in 30-80% of female patients. Most patients have well-developed breasts, which is in sharp contrast to the breast shrinkage of those who have undergone natural menopause. Spontaneous galactorrhea is rare, and milk can only be seen flowing out by squeezing the nipples. Those with high blood PRL levels do not experience galactorrhea, which may be due to the fact that high PRL strongly inhibits the function of the gonads and significantly reduces the estrogen level. Patients with this disease have true galactorrhea, with liquid flowing out of both nipples. It is a milky or turbid white liquid, rich in casein, whey protein and lactose, and should be distinguished from pseudogalactorrhea.

Hyperprolactinemia must be treated early to avoid harm. Experts point out that hyperprolactinemia has many dangers, but everyone must choose the appropriate treatment method based on their own actual situation to avoid harm from the disease.

Hyperprolactinemia can cause significant osteoporosis, which may be due to the decrease in estrogen levels, but some people also believe that PRL itself has a negative impact on bone density. In addition to the above manifestations, high PRLemia caused by pituitary PRL tumors also has a series of manifestations caused by the mass effect of the tumor and the invasion of the tumor into the adjacent brain tissue, such as headaches and visual field defects.